Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361420 | 0.83 | ALDH1A1 (0.74) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11219074 | 0.78 | RAB9A (0.58) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL11223273 | 0.77 | MAPT (0.63) | MAPTPTPN1ALDH1A1PKMNPC1 | |
| SCHEMBL10980417 | 0.77 | MEN1 (0.50) | MAPTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11231406 | 0.76 | RAB9A (0.57) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL11220020 | 0.76 | RAB9A (0.57) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL19724747 | 0.76 | MAPT (0.58) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL19981508 | 0.76 | MAPT (0.58) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL2631604 | 0.75 | RAB9A (0.56) | MAPTALDH1A1PKMNPC1RAB9A | |
| SCHEMBL10812910 | 0.75 | RAB9A (0.68) | MAPTALDH1A1PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |