SCHEMBL8918979

SCHEMBL8918979

CCOC1(OCC)NC(=N)c2ccc(Sc3ccc(C(C)(C)C)cc3)cc21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.32
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
PTGIR P43119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918041 0.91 DHFR (0.32) DHFRMAOAMAOBPTGIR
SCHEMBL8919866 0.88 MAOA (0.33) MAOAMAOBPTGIR
SCHEMBL7824864 0.86 NPC1 (0.31)
SCHEMBL7827395 0.78 CYP1A2 (0.33)
SCHEMBL8920434 0.78 DHFR (0.36) DHFR
SCHEMBL8919057 0.78 MAOA (0.33) MAOAMAOBPTGIR
SCHEMBL8919084 0.77 DHFR (0.35) DHFR
SCHEMBL7824998 0.74
SCHEMBL7828075 0.72 AKR1B1 (0.36)
SCHEMBL7824782 0.72 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed