Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991823 | 0.76 | DRD2 (0.35) | DRD2SLC6A4HTR2C | |
| SCHEMBL4676653 | 0.74 | SLC6A4 (0.55) | DRD2SLC6A4CYP2A6 | |
| SCHEMBL5584733 | 0.72 | HTR2C (0.62) | SLC6A4HTR2CPDK2PDK4 | |
| SCHEMBL3208274 | 0.71 | HTR2C (0.60) | SLC6A4HTR2C | |
| SCHEMBL8917845 | 0.71 | KCNA3 (0.36) | DRD2SLC6A4HTR2CPDK2PDK4 | |
| SCHEMBL8916906 | 0.70 | DRD2 (0.38) | DRD2SLC6A4 | |
| SCHEMBL8920077 | 0.70 | MAPT (0.45) | DRD2SLC6A4CYP2A6 | |
| SCHEMBL8917269 | 0.70 | ADRB1 (0.34) | CYP1A2CYP2A6 | |
| SCHEMBL2716393 | 0.69 | MAP3K14 (0.39) | HTR2CCYP1A2CYP2A6 | |
| SCHEMBL8404365 | 0.68 | CYP1A2 (0.48) | CYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |