Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919053 | 1.00 | THRB (0.40) | THRBGLO1CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL6131246 | 0.88 | THRB (0.50) | THRBGLO1ALDH1A1TSHRNPSR1 | |
| SCHEMBL11706145 | 0.81 | ALDH1A1 (0.56) | THRBGLO1CYP2D6CYP2C19ALDH1A1 | |
| Methacrylic Acid SCHEMBL27319244 | 0.80 | GLO1 (0.44) | THRBGLO1CYP2D6CYP2C19ALDH1A1 | |
| Acrylic Acid Ethyl Ester SCHEMBL11822595 | 0.80 | TSHR (0.41) | THRBGLO1ALDH1A1TSHRNPSR1 | |
| SCHEMBL111294 | 0.80 | — | — | |
| SCHEMBL111293 | 0.80 | — | — | |
| SCHEMBL12789347 | 0.80 | — | — | |
| SCHEMBL15638175 | 0.79 | ALDH1A1 (0.37) | ALDH1A1TSHR | |
| Alcohol SCHEMBL28190975 | 0.78 | ALDH1A1 (0.42) | THRBALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591805-A | MALEIC ANHYDRIDE-CYCLOOCTENE COPOLYMER CURED WITH HYDROXY, ACID, EPOXY OR AMINE COMPOUNDS, CLEAR COATS | THE SHERWIN-WILLIAMS COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5589560-A | Curable compositions incorporating anhydride-functional polymers derived from alkenyl succinic anhydride | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-12-31 | — | — | US | disclosed |
| US-5492976-A | CLEAR COATS; AUTOMOBILES | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5480951-A | COATINGS | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| US-5444139-A | Copolymer of alkenyl succinic anhydride, methacrylic ester and /or another unsaturated monomer other than methacrylic ester | THE SHERWIN-WILLIAMS COMPANY (US) | 1995-08-22 | — | — | US | disclosed |