SCHEMBL8919166

SCHEMBL8919166

CCOc1cccc2c1C(=N)NC21OCCO1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.39
HTR2A P28223 2/20 0.36
HTR2B P41595 2/20 0.36
ADRB2 P07550 1/20 0.36
HTR1A P08908 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
ADRA1A P35348 1/20 0.36
SLC6A3 Q01959 1/20 0.36
ALDH1A1 P00352 6/20 0.34
KDM4E B2RXH2 4/20 0.34
MEN1 O00255 4/20 0.34
MAPT P10636 4/20 0.34
KMT2A Q03164 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34
BLM P54132 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
DDB1 Q16531 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27455763 0.90 PRKCA (0.34) HTR2BPOLBNPSR1GAACYP2A6
SCHEMBL27427704 0.88 PRKCA (0.38) KDM4EMAPTKMT2APOLBTSHR
SCHEMBL8919749 0.86 PRKCA (0.43) HTR2BSLC6A3MEN1MAPTKMT2A
SCHEMBL8919132 0.86 PRKCA (0.43) HTR2BSLC6A3MEN1MAPTKMT2A
SCHEMBL8921478 0.85 TXNRD1 (0.42) PDK2HTR1AALDH1A1KDM4EKMT2A
SCHEMBL8919172 0.83 PDK2 (0.38) PDK2HTR2AHTR2BADRB2HTR1A
SCHEMBL8918250 0.80 PDE7A (0.31) PDK2
SCHEMBL8919955 0.80 ALDH1A1 (0.36) PDK2HTR2AHTR2BADRB2HTR1A
SCHEMBL7824104 0.79 PDK2 (0.43) PDK2ALDH1A1KDM4EMEN1MAPT
SCHEMBL8917731 0.78 SLC6A2 (0.34) HTR1ASLC6A2SLC6A4SLC6A3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed