Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916271 | 0.89 | CA1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8916161 | 0.89 | NR3C1 (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8917772 | 0.88 | CA1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8918872 | 0.88 | KDM1A (0.45) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8916626 | 0.87 | CA1 (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8917793 | 0.87 | CA1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8918908 | 0.86 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8918164 | 0.85 | PPARG (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8918757 | 0.85 | ALDH1A1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8917188 | 0.85 | PLAU (0.48) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |