Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.48 |
| ▸ | PLAT | P00750 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.41 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918164 | 0.90 | PPARG (0.41) | PLAUPLATMAPTPPARGNR3C1 | |
| SCHEMBL8916271 | 0.88 | CA1 (0.43) | L3MBTL1ALDH1A1PPARGNR3C1AR | |
| SCHEMBL8916161 | 0.86 | NR3C1 (0.44) | ALDH1A1ALOX15NR3C1ARPGR | |
| SCHEMBL8917334 | 0.86 | MEN1 (0.42) | PLAUL3MBTL1GAAMAPTKDM4E | |
| SCHEMBL8918908 | 0.85 | CA1 (0.41) | L3MBTL1ALDH1A1PPARGNR3C1AR | |
| SCHEMBL8917772 | 0.85 | CA1 (0.43) | GAANR3C1ARPGRESR2 | |
| SCHEMBL8919219 | 0.85 | CA1 (0.45) | GAAALDH1A1PPARGNR3C1AR | |
| SCHEMBL8918872 | 0.85 | KDM1A (0.45) | GAAMAPTPPARGNR3C1AR | |
| SCHEMBL8916626 | 0.85 | CA1 (0.46) | GAAALDH1A1PPARGNR3C1AR | |
| SCHEMBL8918757 | 0.85 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1PPARGNR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696143-A | ARTHRITIS THERAPY | G.D. SEARLE & CO. | 1997-12-09 | — | — | US | disclosed |