Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919243 | 0.79 | L3MBTL1 (0.38) | L3MBTL1GRIN2BOPRM1 | |
| Oxalic Acid SCHEMBL8919236 | 0.78 | MEN1 (0.41) | L3MBTL1GRIN2BCYP2C9CYP2C19HTR2B | |
| Hydrochloric Acid SCHEMBL8922908 | 0.73 | MAPK14 (0.41) | GRIN2BCYP2C9CYP2C19MAPK14MEN1 | |
| SCHEMBL9391461 | 0.72 | L3MBTL1 (0.43) | L3MBTL1CYP2C9CYP2C19HTR2BMAPK14 | |
| Hydrochloric Acid SCHEMBL7470749 | 0.71 | L3MBTL1 (0.43) | L3MBTL1CYP2C9CYP2C19HTR2BMAPK14 | |
| Hydrochloric Acid SCHEMBL7470963 | 0.71 | HTT (0.53) | L3MBTL1CYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL9207045 | 0.71 | CCR3 (0.41) | L3MBTL1GRIN2BCYP2C9CYP2C19HTR2B | |
| Hydrochloric Acid SCHEMBL8918415 | 0.70 | CCR3 (0.41) | L3MBTL1GRIN2BCYP2C9CYP2C19HTR2B | |
| SCHEMBL8922923 | 0.70 | CRBN (0.48) | GRIN2BCHIA | |
| Hydrochloric Acid SCHEMBL8919035 | 0.70 | GRIN2B (0.39) | L3MBTL1GRIN2BMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |