Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18031229 | 0.87 | CRBN (0.48) | TDP1L3MBTL1LMNASMN1; SMN2CA12 | |
| SCHEMBL22411387 | 0.83 | SRD5A1 (0.42) | TDP1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL11123134 | 0.82 | LMNA (0.47) | TDP1L3MBTL1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL8920608 | 0.82 | CA12 (0.47) | TDP1L3MBTL1LMNARAB9ACA12 | |
| SCHEMBL11120527 | 0.81 | NR3C1 (0.38) | TDP1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL18033416 | 0.80 | HSD17B2 (0.47) | HSD17B2UBE2NCASP6TDP1L3MBTL1 | |
| SCHEMBL22412138 | 0.79 | KMT2A (0.46) | LMNASMN1; SMN2NPC1RAB9ACA12 | |
| SCHEMBL22411409 | 0.78 | ALOX15 (0.51) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL14642141 | 0.76 | CYP11B1 (0.41) | L3MBTL1NPC1CA9 | |
| SCHEMBL7294192 | 0.75 | CRBN (0.56) | L3MBTL1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591751-A | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0636128-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019339-A1 | PIPERAZINOCARBONYLCARBOSTYRILS AS PERIPHERAL VASODILATORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-01 | — | — | WO | disclosed |