SCHEMBL8919281

SCHEMBL8919281

CCOc1ccc2c(c1)C(=N)NC21OCCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.40
KDM4E B2RXH2 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CYP3A4 P08684 2/20 0.40
ALOX12 P18054 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
PDK2 Q15119 2/20 0.39
MAPT P10636 5/20 0.35
NPSR1 Q6W5P4 2/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918297 0.89 PDK2 (0.39) ALDH1A1KDM4ETDP1LMNAMEN1
SCHEMBL8921438 0.86 PDK2 (0.39) KDM4ETDP1LMNACYP3A4CYP1A2
SCHEMBL8919289 0.83 ALDH1A1 (0.39) ALDH1A1KDM4ETDP1LMNAMEN1
SCHEMBL8921046 0.78 MAOA (0.46) TDP1HPGDPDK2MAPTPIM1
SCHEMBL7827487 0.77 ALDH1A1 (0.43) ALDH1A1KDM4ETDP1LMNAMEN1
SCHEMBL7816180 0.76 ALDH1A1 (0.43) ALDH1A1KDM4ETDP1LMNAMEN1
SCHEMBL8920310 0.76 PDK2 (0.44) LMNAPDK2
SCHEMBL8918856 0.76 PDK2 (0.44) LMNAPDK2
SCHEMBL8921171 0.76 ALDH1A1 (0.38) ALDH1A1KDM4ETDP1LMNAMEN1
SCHEMBL8920391 0.75 CYP3A4 (0.36) ALDH1A1KDM4ETDP1LMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
CN-1114431-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS (JP) 1996-01-03 CN disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed