Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922239 | 0.89 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3CYP2D6CYP2C19 | |
| SCHEMBL9540219 | 0.88 | CCKBR (0.47) | CYP2C19 | |
| SCHEMBL9541670 | 0.87 | CCKBR (0.51) | CYP2C19 | |
| SCHEMBL8919676 | 0.85 | CCKBR (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8920848 | 0.85 | CYP2C19 (0.47) | CYP2C19 | |
| SCHEMBL9540184 | 0.84 | CYP2C19 (0.43) | CYP2C19 | |
| SCHEMBL9541664 | 0.84 | CCKBR (0.48) | CYP2C19 | |
| SCHEMBL9544115 | 0.80 | CYP2C19 (0.46) | CYP2C19 | |
| SCHEMBL9542926 | 0.80 | CCKBR (0.49) | CYP2C19 | |
| SCHEMBL9541282 | 0.78 | CCKBR (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |