Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919982 | 0.76 | MMP13 (0.46) | ALDH1A1POLBRAB9ACA12CA1 | |
| SCHEMBL8919909 | 0.74 | SERPINE1 (0.36) | MYCSERPINE1MAPTKDM4EALDH1A1 | |
| SCHEMBL8772646 | 0.71 | FDFT1 (0.56) | — | |
| SCHEMBL8417915 | 0.69 | ACACB (0.37) | ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL8421763 | 0.67 | EGFR (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6702062 | 0.66 | SERPINE1 (0.80) | SERPINE1KDM4EALDH1A1POLBTSHR | |
| SCHEMBL27897792 | 0.65 | SERPINE1 (0.57) | MYCSERPINE1KDM4EALDH1A1POLB | |
| SCHEMBL27586214 | 0.65 | KDM4E (0.63) | SERPINE1KDM4EALDH1A1POLBTSHR | |
| SCHEMBL7522651 | 0.65 | CA12 (0.58) | MYCSERPINE1MAPTKDM4EALDH1A1 | |
| SCHEMBL8919905 | 0.64 | FDFT1 (0.41) | ALDH1A1POLBRAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691349-A | ANTICHOLESTEROL AGENTS; ATHEROSCLEROSIS | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |