Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49946 | 0.63 | KMT2A (0.57) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2TSHR | |
| SCHEMBL23022737 | 0.63 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1RXFP1HSD17B10SMN1; SMN2 | |
| SCHEMBL3718670 | 0.61 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL8921089 | 0.61 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL21232988 | 0.61 | MAPK1 (0.47) | ALDH1A1RXFP1SMN1; SMN2MAPTTP53 | |
| SCHEMBL7300318 | 0.60 | MEN1 (0.59) | RXFP1SMN1; SMN2HTTGAAMEN1 | |
| SCHEMBL6971648 | 0.59 | HTT (0.64) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL48934 | 0.59 | SMN1; SMN2 (0.68) | L3MBTL1ALDH1A1SMN1; SMN2HTTGAA | |
| SCHEMBL26854536 | 0.59 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1RXFP1HSD17B10SMN1; SMN2 | |
| SCHEMBL6172380 | 0.58 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1HSD17B10SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616579-A | ADMINISTERING TO MAMMALS TO PREVENT GASTRIC ULCER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0562833-B1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO CO (JP) | 1996-05-08 | — | — | EP | disclosed |
| CN-1081437-A | Antiulcer pyridine oxygen derivative, their preparation method and purposes | SANKYO CO (JP) | 1994-02-02 | — | — | CN | disclosed |
| EP-0562833-A1 | Anti-ulcer pyridyloxy derivatives, their preparation and uses | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |