Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 4/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126423 | 0.89 | DPP4 (0.57) | DPP4LMNATOP2ATOP2BKDM4E | |
| SCHEMBL8922023 | 0.87 | DPP4 (0.62) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| Enoxacin SCHEMBL8922307 | 0.86 | LMNA (0.74) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL311935 | 0.86 | LMNA (0.68) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL8920926 | 0.84 | DPP4 (0.54) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL11020192 | 0.83 | LMNA (0.64) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL10377708 | 0.78 | DPP4 (0.66) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL10377719 | 0.77 | DPP4 (0.65) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL10377337 | 0.77 | DPP4 (0.65) | DPP4LMNACYP2C9ATP6V1B2TBXA2R | |
| SCHEMBL9686438 | 0.77 | DPP4 (0.68) | DPP4LMNACYP2C9ATP6V1B2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672600-A | Antimicrobial dithiocarbamoyl quinolones | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-5387748-A | Antimicrobial dithiocarbamoyl quinolones | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1990004591-A1 | NOVEL ANTIMICROBIAL DITHIOCARBAMOYL QUINOLONES | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1990-05-03 | — | — | WO | disclosed |
| EP-0366643-A2 | Novel antimicrobial dithiocarbamoyl quinolones | Norwich Eaton Pharmaceuticals, Inc. (US) | 1990-05-02 | — | — | EP | disclosed |