Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | APAF1 | O14727 | 3/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | TDP2 | O95551 | 4/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | CTH | P32929 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269145 | 0.86 | TDP2 (0.55) | RAB9APOLBAPAF1PAX8MEN1 | |
| SCHEMBL8919698 | 0.77 | GAA (0.60) | PAX8MEN1KMT2ACDC25BTDP2 | |
| SCHEMBL16432617 | 0.73 | MEN1 (0.57) | RAB9APOLBAPAF1PAX8MEN1 | |
| Anthraquinone SCHEMBL1901249 | 0.72 | MEN1 (1.00) | RAB9APOLBAPAF1PAX8MEN1 | |
| Anthraquinone SCHEMBL14943 | 0.72 | MEN1 (1.00) | RAB9APOLBAPAF1PAX8MEN1 | |
| Anthraquinone SCHEMBL29358690 | 0.72 | MEN1 (1.00) | RAB9APOLBAPAF1PAX8MEN1 | |
| SCHEMBL10752577 | 0.71 | CES1 (0.59) | RAB9APOLBAPAF1PAX8KMT2A | |
| SCHEMBL2922398 | 0.70 | PDE10A (0.52) | SMN1; SMN2MAPK1KDM4EHTTALDH1A1 | |
| Anthraquinone SCHEMBL8081485 | 0.69 | MEN1 (0.92) | RAB9APOLBAPAF1PAX8MEN1 | |
| Anthraquinone SCHEMBL6415478 | 0.69 | MEN1 (0.92) | RAB9APOLBAPAF1PAX8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605905-A | DIAZAQUINOMICIN ANALOGS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1997-02-25 | — | — | US | disclosed |
| EP-0574195-A1 | Antitumoral aza- and diazaanthracenes | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1993-12-15 | — | — | EP | disclosed |