Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP2 | O95551 | 3/20 | 0.55 |
| ▸ | NSD2 | O96028 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | S100A4 | P26447 | 5/20 | 0.51 |
| ▸ | CDC25B | P30305 | 2/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915061 | 0.79 | GAA (0.86) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL8920440 | 0.77 | RAB9A (0.56) | TDP2NSD2PAX8TDP1PLCG1 | |
| SCHEMBL29551149 | 0.77 | GAA (1.00) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL579998 | 0.77 | GAA (1.00) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL5915065 | 0.77 | TDP2 (0.81) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL30774319 | 0.77 | GAA (1.00) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL6269145 | 0.77 | TDP2 (0.55) | GAATDP2NSD2PAX8MEN1 | |
| SCHEMBL29746876 | 0.75 | GAA (0.78) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL1103717 | 0.75 | GAA (0.78) | GAATDP2NSD2PAX8TDP1 | |
| SCHEMBL30704440 | 0.74 | NSD2 (0.53) | GAATDP2NSD2PAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605905-A | DIAZAQUINOMICIN ANALOGS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1997-02-25 | — | — | US | disclosed |
| EP-0574195-A1 | Antitumoral aza- and diazaanthracenes | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1993-12-15 | — | — | EP | disclosed |