Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | CTH | P32929 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920440 | 0.86 | RAB9A (0.56) | TDP2NSD2IDO1CTHALDH1A1 | |
| SCHEMBL7808065 | 0.78 | TDP2 (0.39) | TDP2NSD2IDO1CTHALDH1A1 | |
| SCHEMBL8919698 | 0.77 | GAA (0.60) | TDP2NSD2IDO1PAX8MEN1 | |
| SCHEMBL6407655 | 0.70 | IDO1 (0.54) | TDP2NSD2IDO1CTHALDH1A1 | |
| SCHEMBL25071563 | 0.67 | CASP3 (0.41) | TDP2NSD2IDO1CTHUPP1 | |
| SCHEMBL2922398 | 0.67 | PDE10A (0.52) | ALDH1A1GAA | |
| SCHEMBL16736421 | 0.61 | CA12 (0.55) | ALDH1A1AOC3CA12CA9CA1 | |
| SCHEMBL16416442 | 0.60 | IDO1 (0.40) | TDP2NSD2IDO1CTHALDH1A1 | |
| SCHEMBL5157080 | 0.59 | TDP2 (0.33) | TDP2NSD2IDO1CTHALDH1A1 | |
| SCHEMBL24404193 | 0.57 | IDO1 (0.52) | TDP2IDO1ALDH1A1APAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050227266-A1 | Biomarker:compound correlations in cancer diagnosis and therapy | APPLIED GENOMICS, INC. | 2005-10-13 | — | — | US | claimed |
| WO-2005085863-A2 | BIOMARKER: COMPOUND CORRELATIONS IN CANCER DIAGNOSIS AND THERAPY | APPLIED GENOMICS, INC. (US) | 2005-09-15 | — | — | WO | claimed |