Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921657 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL8919472 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2AKLK7KLK5 | |
| SCHEMBL8920834 | 0.93 | APP (0.39) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921550 | 0.93 | APP (0.39) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8920849 | 0.93 | APP (0.39) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921553 | 0.93 | APP (0.39) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921535 | 0.93 | APP (0.39) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921588 | 0.91 | CTSK (0.41) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921597 | 0.91 | CTSK (0.41) | MAPTMEN1KMT2AL3MBTL1APP | |
| SCHEMBL8921748 | 0.91 | CTSK (0.41) | MAPTMEN1KMT2AL3MBTL1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |