Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922273 | 0.84 | SIRT1 (0.59) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8922195 | 0.84 | PTPN1 (0.62) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21510762 | 0.83 | PTPN1 (0.66) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7920846 | 0.81 | POLB (0.76) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9182279 | 0.78 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL7922647 | 0.76 | KMT2A (0.68) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL12061016 | 0.75 | PTPN1 (0.51) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2024299 | 0.75 | PTPN1 (0.51) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16316028 | 0.74 | NPC1 (0.59) | PTPN1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19066021 | 0.73 | KDM1A (0.64) | PTPN1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |