SCHEMBL8920860

SCHEMBL8920860

N=C1NC2(CCCOO2)c2cccc(Oc3ccccc3)c21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.32
SLC6A4 P31645 4/20 0.32
SLC6A3 Q01959 4/20 0.32
HTR1A P08908 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918925 0.84 TXNRD1 (0.38)
SCHEMBL8919068 0.82 SLC6A2 (0.32) SLC6A2SLC6A4SLC6A3HTR1A
SCHEMBL8919056 0.81 PDK2 (0.34) SLC6A2SLC6A4SLC6A3HTR1A
SCHEMBL8917814 0.80 PDE7A (0.33)
SCHEMBL8921238 0.77 PRKCA (0.38) SLC6A3
SCHEMBL8920277 0.77 PRKCA (0.38) SLC6A3
SCHEMBL8918917 0.77 MAOA (0.37) SLC6A2SLC6A4SLC6A3
SCHEMBL8919302 0.77 MAOA (0.37) SLC6A2SLC6A4SLC6A3
SCHEMBL9090620 0.77 TXNRD1 (0.36)
SCHEMBL8917731 0.75 SLC6A2 (0.34) SLC6A2SLC6A4SLC6A3HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed