Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 18/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920904 | 1.00 | CCKBR (0.41) | CCKBRPOLQDRD2DRD4DRD3 | |
| SCHEMBL8921471 | 0.94 | CCKBR (0.45) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8920279 | 0.94 | CCKBR (0.45) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8920274 | 0.94 | CCKBR (0.45) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8921281 | 0.93 | CCKBR (0.47) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8922626 | 0.92 | CCKBR (0.49) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8922615 | 0.92 | CCKBR (0.49) | CCKBRDRD2DRD4DRD3 | |
| SCHEMBL8923527 | 0.92 | CCKBR (0.41) | CCKBR | |
| SCHEMBL8920335 | 0.92 | CCKBR (0.35) | CCKBRPOLQ | |
| SCHEMBL8920329 | 0.92 | CCKBR (0.35) | CCKBRPOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |