Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920335 | 1.00 | CCKBR (0.35) | CCKBRTACR1POLQPAX8CCR5 | |
| SCHEMBL8919265 | 0.94 | CCKBR (0.38) | CCKBR | |
| SCHEMBL8920689 | 0.93 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8920699 | 0.93 | CCKBR (0.37) | CCKBR | |
| SCHEMBL8921431 | 0.93 | CCKBR (0.42) | CCKBRCCR5 | |
| SCHEMBL8921428 | 0.93 | CCKBR (0.42) | CCKBRCCR5 | |
| SCHEMBL8920904 | 0.92 | CCKBR (0.41) | CCKBRPOLQ | |
| SCHEMBL8920898 | 0.92 | CCKBR (0.41) | CCKBRPOLQ | |
| SCHEMBL8923527 | 0.92 | CCKBR (0.41) | CCKBR | |
| SCHEMBL8922438 | 0.90 | OPRM1 (0.35) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |
| WO-1993015059-A1 | 3-PHENYLUREIDO-AZEPIN-2-ONES AND -BENZAZEPIN-2-ONES USEFUL AS CHOLECYSTOKININ ANTAGONISTS | PFIZER INC. (US) | 1993-08-05 | — | — | WO | disclosed |