Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 9/20 | 0.43 |
| ▸ | LOX | P28300 | 6/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920977 | 1.00 | LOXL2 (0.43) | LOXL2LOXAOC3CHRNB2CHRNA4 | |
| SCHEMBL10674128 | 0.78 | LOXL2 (0.46) | LOXL2LOXCHRNB2CHRNA4NOS1 | |
| SCHEMBL10375014 | 0.75 | LOXL2 (0.62) | LOXL2LOXCHRNB2CHRNA4HTR1A | |
| SCHEMBL8920035 | 0.74 | ADRA2C (0.50) | LOXL2LOXAOC3CHRNB2CHRNA4 | |
| SCHEMBL8920041 | 0.74 | ADRA2C (0.50) | LOXL2LOXAOC3CHRNB2CHRNA4 | |
| SCHEMBL10375013 | 0.73 | LOXL2 (0.47) | LOXL2LOXCHRNB2CHRNA4NOS1 | |
| SCHEMBL15015273 | 0.73 | LOXL2 (0.43) | LOXL2LOXCHRNB2CHRNA4NOS1 | |
| SCHEMBL9091019 | 0.73 | CYP2D6 (0.31) | — | |
| SCHEMBL8078636 | 0.73 | ADRA2C (0.52) | LOXL2LOXHRH3ALDH1A1 | |
| SCHEMBL8078640 | 0.73 | ADRA2C (0.52) | LOXL2LOXHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616579-A | ADMINISTERING TO MAMMALS TO PREVENT GASTRIC ULCER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |