SCHEMBL8920976

SCHEMBL8920976

CC1OC2(NC(=N)c3ccc(Cl)cc32)O1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 5/20 0.36
AKR1A1 P14550 2/20 0.36
PGR P06401 3/20 0.33
NR3C1 P04150 1/20 0.33
AR P10275 1/20 0.33
PDK2 Q15119 1/20 0.33
PPOX P50336 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
CYP46A1 Q9Y6A2 1/20 0.30
PDE7A Q13946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918851 0.88 PPOX (0.32) PGRNR3C1ARPPOX
SCHEMBL8922236 0.83
SCHEMBL8920969 0.78 AKR1A1 (0.37) AKR1B1AKR1A1PGRPDK2PPOX
SCHEMBL8920583 0.74 PDK2 (0.40) PDK2MEN1KMT2A
SCHEMBL7827374 0.71 AKR1B1 (0.39) AKR1B1AKR1A1PGRPDK2PPOX
SCHEMBL8919366 0.71 PDK2 (0.34) PDK2
SCHEMBL8920209 0.71 NPC1 (0.31)
SCHEMBL8921050 0.67 MAOB (0.40) PDK2
SCHEMBL7828075 0.67 AKR1B1 (0.36) AKR1B1AKR1A1PGRPDK2PPOX
SCHEMBL8918847 0.66 PPOX (0.37) AKR1B1AKR1A1PDK2PPOXPDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed