Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3550509 | 0.74 | L3MBTL1 (0.40) | L3MBTL1KDM4EATMALDH1A1OPRD1 | |
| SCHEMBL31369757 | 0.73 | KIF11 (0.47) | KMT2AL3MBTL1PPARG | |
| SCHEMBL1317427 | 0.73 | ADRA2B (0.51) | MEN1KMT2AL3MBTL1OPRK1KCNH2 | |
| SCHEMBL29110818 | 0.72 | L3MBTL1 (0.41) | SMN1; SMN2CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL16210255 | 0.72 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL16210253 | 0.72 | MEN1 (0.47) | SMN1; SMN2MEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL9773231 | 0.71 | KDM4E (0.46) | KMT2AL3MBTL1KDM4EATMALDH1A1 | |
| SCHEMBL8921038 | 0.71 | L3MBTL1 (0.43) | SMN1; SMN2MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10429884 | 0.71 | PPARG (0.46) | SMN1; SMN2MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL16188322 | 0.70 | MEN1 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |