Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464154 | 0.84 | L3MBTL1 (0.56) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7464454 | 0.84 | L3MBTL1 (0.73) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL8920264 | 0.83 | MEN1 (0.66) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7463414 | 0.83 | L3MBTL1 (0.60) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7461852 | 0.83 | L3MBTL1 (0.70) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7467356 | 0.82 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL7459655 | 0.82 | ALDH1A1 (0.58) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL4735039 | 0.82 | L3MBTL1 (0.56) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7459336 | 0.81 | PRMT5 (0.56) | MEN1KMT2AMAPTLMNAPRMT5 | |
| SCHEMBL7468316 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2AMAPTLMNAPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0685466-A1 | 3-Heteroaliphatyle-and 3-hetero-(aryle)-aliphatyle-2(1H)-quinolone derivatives | CIBA-GEIGY AG (CH) | 1995-12-06 | — | — | EP | disclosed |