Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921377 | 0.79 | ALDH1A1 (0.46) | RAB9ANPC1L3MBTL1THRBALDH1A1 | |
| SCHEMBL8921188 | 0.79 | KMT2A (0.46) | L3MBTL1ALDH1A1KMT2AHPGDHSD17B10 | |
| SCHEMBL8921973 | 0.78 | KMT2A (0.39) | ALDH1A1KMT2ATSHRHPGDTP53 | |
| SCHEMBL7461299 | 0.78 | KMT2A (0.53) | RAB9ANPC1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8920748 | 0.78 | KMT2A (0.44) | RAB9AL3MBTL1ALDH1A1KMT2ATSHR | |
| SCHEMBL7456883 | 0.77 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KMT2ATP53MAPT | |
| SCHEMBL8922387 | 0.76 | MAPT (0.50) | RAB9AL3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL8923389 | 0.76 | ALDH1A1 (0.43) | RAB9ANPC1L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8921264 | 0.76 | CYP4F2 (0.47) | RAB9ANPC1ALDH1A1KMT2AHPGD | |
| SCHEMBL7462636 | 0.76 | KDM4E (0.48) | RAB9ANPC1L3MBTL1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |