Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922387 | 0.91 | MAPT (0.50) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8923079 | 0.90 | ALDH1A1 (0.43) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8921264 | 0.84 | CYP4F2 (0.47) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8921852 | 0.84 | POLB (0.44) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8919875 | 0.84 | ALDH1A1 (0.40) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8921973 | 0.82 | KMT2A (0.39) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7462894 | 0.81 | KDM4E (0.64) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8923389 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL8924828 | 0.80 | SMN1; SMN2 (0.43) | KMT2AMEN1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL8921372 | 0.78 | RAB9A (0.46) | KMT2AMEN1L3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |