Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923316 | 0.80 | MEN1 (0.42) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8920264 | 0.80 | MEN1 (0.66) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8921372 | 0.79 | RAB9A (0.46) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL7456883 | 0.78 | ALDH1A1 (0.53) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL7459783 | 0.78 | ALDH1A1 (0.53) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8922387 | 0.78 | MAPT (0.50) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL7461619 | 0.77 | ALDH1A1 (0.52) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL7462894 | 0.77 | KDM4E (0.64) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8920748 | 0.77 | KMT2A (0.44) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL8923079 | 0.77 | ALDH1A1 (0.43) | KMT2AMEN1LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633379-A | N-METHYLASPARTIC ACID ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |