Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8568520 | 0.84 | BACE1 (0.56) | BACE1HTTMAPTPOLBSMN1; SMN2 | |
| SCHEMBL8921373 | 0.81 | HTT (0.64) | BACE1HTTMAPTPOLBSMN1; SMN2 | |
| SCHEMBL26914710 | 0.78 | MAPT (0.58) | BACE1HTTMAPTMEN1KMT2A | |
| SCHEMBL8569474 | 0.77 | HTT (0.49) | BACE1HTTMAPTPOLBSMN1; SMN2 | |
| SCHEMBL8561698 | 0.76 | NSD2 (0.50) | HTTSMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL8563864 | 0.76 | NSD2 (0.49) | POLBSMN1; SMN2CYP1A2CYP3A4LMNA | |
| SCHEMBL8596102 | 0.76 | HCAR3 (0.42) | HTTMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL4743191 | 0.76 | HTT (0.61) | HTTMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL8566712 | 0.75 | CYP19A1 (0.43) | HTTMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2572082 | 0.75 | HTT (0.50) | HTTMAPTPOLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |