Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561698 | 0.82 | NSD2 (0.50) | HTTHPGDCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8562600 | 0.81 | LMNA (0.47) | HTTHPGDMAPK1KMT2AMAPT | |
| SCHEMBL8565008 | 0.80 | HPGD (0.54) | HTTHPGDCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8599108 | 0.79 | SMN1; SMN2 (0.43) | HTTHPGDCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8567191 | 0.78 | NAPRT (0.50) | HTTCYP3A4CYP1A2CYP2C19KMT2A | |
| SCHEMBL8562423 | 0.78 | RAB9A (0.52) | HTTKMT2AMAPTEGLN1LMNA | |
| SCHEMBL8565140 | 0.78 | HTT (0.55) | HTTHPGDCYP3A4CYP1A2CYP2C19 | |
| SCHEMBL922492 | 0.77 | NSD2 (0.66) | HPGDMAPK1NSD2KMT2AGAA | |
| SCHEMBL8598538 | 0.77 | NAAA (0.45) | HTTHPGDLMNAL3MBTL1 | |
| SCHEMBL8921373 | 0.76 | HTT (0.64) | HTTHPGDCYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |