Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627277 | 0.80 | KCNJ1 (0.38) | ALDH1A1HPGDCYP11B2KCNJ1 | |
| SCHEMBL8921263 | 0.78 | KCNJ1 (0.42) | KDM4EPOLBKCNJ1LMNAMEN1 | |
| SCHEMBL14565127 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4ECYP11B2PKM | |
| SCHEMBL8920270 | 0.76 | KMT2A (0.52) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL8626022 | 0.76 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EHTTSMN1; SMN2 | |
| SCHEMBL14565146 | 0.74 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP11B2PKMKCNJ1 | |
| SCHEMBL19023154 | 0.72 | HPGD (0.37) | ALDH1A1HPGDKDM4ECYP11B2HTT | |
| SCHEMBL8473870 | 0.69 | HSD17B10 (0.34) | ALDH1A1HPGDKDM4ECYP11B2HTT | |
| SCHEMBL21377510 | 0.69 | HSD17B10 (0.53) | ALDH1A1HPGDKDM4EHTTPKM | |
| SCHEMBL8624679 | 0.69 | HRH3 (0.33) | ALDH1A1HPGDKDM4ECYP11B2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |