Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560819 | 0.85 | HPGD (0.53) | L3MBTL1HPGDKDM4EMAPTCYP1A2 | |
| SCHEMBL8599626 | 0.82 | HPGD (0.50) | TP53L3MBTL1HPGDALDH1A1KDM4E | |
| SCHEMBL8599144 | 0.80 | SMN1; SMN2 (0.46) | L3MBTL1HPGDALDH1A1KDM4EHTT | |
| SCHEMBL8598657 | 0.80 | HPGD (0.50) | TP53L3MBTL1HPGDALDH1A1KDM4E | |
| SCHEMBL8601173 | 0.80 | ALDH1A1 (0.42) | TP53HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8563341 | 0.79 | MAPT (0.49) | TP53HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8597788 | 0.79 | GSK3A (0.46) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8561968 | 0.78 | MAP2K3 (0.49) | TP53HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8565819 | 0.76 | HSD17B10 (0.49) | TP53HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL8599003 | 0.75 | KDM4E (0.37) | HPGDALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |