Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600621 | 0.83 | LMNA (0.41) | SMN1; SMN2HPGDALDH1A1HTTKDM4E | |
| SCHEMBL8560819 | 0.83 | HPGD (0.53) | HPGDKDM4EGAAL3MBTL1ADORA2A | |
| SCHEMBL8599924 | 0.83 | TLR7 (0.47) | SMN1; SMN2RAB9ANPC1NAAAHPGD | |
| SCHEMBL8601327 | 0.80 | MAPT (0.45) | SMN1; SMN2RAB9ANPC1HPGDALDH1A1 | |
| SCHEMBL8595761 | 0.80 | NAAA (0.45) | SMN1; SMN2RAB9ANPC1NAAAHPGD | |
| SCHEMBL8921743 | 0.80 | TP53 (0.44) | SMN1; SMN2HPGDALDH1A1HTTKDM4E | |
| SCHEMBL8600079 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTKDM4EL3MBTL1 | |
| SCHEMBL3094118 | 0.78 | ADORA3 (0.58) | SMN1; SMN2RAB9ANPC1NAAAHPGD | |
| SCHEMBL8565819 | 0.77 | HSD17B10 (0.49) | SMN1; SMN2RAB9AHPGDALDH1A1HTT | |
| SCHEMBL8563341 | 0.77 | MAPT (0.49) | SMN1; SMN2RAB9AHPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |