Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24548371 | 1.00 | ALDH1A1 (0.55) | ALDH1A1NPSR1LMNAALBPOLB | |
| SCHEMBL10569281 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAALBPOLB | |
| SCHEMBL10553925 | 0.80 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAALBPOLB | |
| SCHEMBL8922794 | 0.79 | ALDH1A1 (0.51) | ALDH1A1NPSR1LMNAADRA1ATK1 | |
| SCHEMBL10551277 | 0.78 | ALDH1A1 (0.49) | ALDH1A1NPSR1LMNAALBPOLB | |
| SCHEMBL10549002 | 0.78 | ALDH1A1 (0.49) | ALDH1A1NPSR1LMNAALBPOLB | |
| SCHEMBL14596607 | 0.78 | LMNA (0.58) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL22992337 | 0.78 | LMNA (0.58) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL762579 | 0.78 | LMNA (0.58) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL23485 | 0.78 | LMNA (0.58) | ALDH1A1LMNAALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |