Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | DHPS | P49366 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426815 | 0.89 | PDE5A (0.43) | ALOX5APFEN1L3MBTL1MAPK1MAPT | |
| SCHEMBL29358551 | 0.81 | MAPK1 (0.40) | MAPK1MAPTLMNATDP1TSHR | |
| SCHEMBL8922098 | 0.81 | ACACB (0.41) | L3MBTL1LMNADHPSS1PR1KDM4E | |
| SCHEMBL8918201 | 0.80 | MAPK1 (0.46) | ALOX5APFEN1ARL3MBTL1MAPK1 | |
| SCHEMBL22207363 | 0.78 | TP53 (0.45) | MAPTLMNATDP1HPGDKDM4E | |
| SCHEMBL3426811 | 0.78 | LMNA (0.39) | L3MBTL1MAPK1MAPTLMNATDP1 | |
| SCHEMBL15322257 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MAPK1MAPTLMNATDP1 | |
| SCHEMBL30240988 | 0.77 | MAPK1 (0.42) | MAPK1MAPTLMNATDP1TSHR | |
| SCHEMBL619078 | 0.77 | MAPK1 (0.42) | MAPK1MAPTLMNATDP1TSHR | |
| SCHEMBL6232474 | 0.77 | MAPK1 (0.42) | MAPK1MAPTLMNATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5679794-A | ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |