SCHEMBL8918201

SCHEMBL8918201

OCCOc1ccccc1-c1nc(O)nc(-c2ccccc2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.46
TP53 P04637 1/20 0.46
RAB9A P51151 1/20 0.46
LMNA P02545 4/20 0.45
HTT P42858 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
MAOB P27338 1/20 0.45
ALOX15 P16050 2/20 0.44
TSHR P16473 2/20 0.44
DHPS P49366 1/20 0.44
HTR7 P34969 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA2B P29275 1/20 0.44
ADORA1 P30542 1/20 0.44
PDE5A O76074 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581724 0.94 MAPK1 (0.51) MAPK1TP53RAB9ALMNAHTT
SCHEMBL8380964 0.89 DHPS (0.48) MAPK1TP53RAB9ASMN1; SMN2DHPS
SCHEMBL8651030 0.89 DHPS (0.48) MAOBDHPSPDE5AMEN1KMT2A
SCHEMBL7258451 0.83 MAOB (0.50) MAPK1TP53RAB9ALMNAHTT
SCHEMBL8922091 0.80 ALOX5AP (0.42) MAPK1RAB9ALMNASMN1; SMN2TSHR
SCHEMBL8918234 0.80 ALDH1A1 (0.56) MAOBDHPSMEN1KMT2AL3MBTL1
SCHEMBL159005 0.79 TP53 (0.69) MAPK1TP53RAB9ALMNAHTT
SCHEMBL29418129 0.79 TP53 (0.69) MAPK1TP53RAB9ALMNAHTT
SCHEMBL9857798 0.76 TP53 (0.65) MAPK1TP53RAB9ALMNAHTT
SCHEMBL1938309 0.75 TP53 (0.57) MAPK1TP53RAB9ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679794-A ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1997-10-21 US disclosed