Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921479 | 0.85 | LAP3 (0.44) | CTSCACP3CYP1A2 | |
| SCHEMBL2575732 | 0.74 | SLC6A4 (0.45) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL11302551 | 0.71 | CTSC (0.47) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL10585788 | 0.71 | CTSC (0.49) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL5908167 | 0.69 | SLC6A4 (0.44) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL8925358 | 0.69 | GGPS1 (0.39) | LMNAHTT | |
| SCHEMBL18703964 | 0.67 | SLC6A4 (0.48) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL4657515 | 0.66 | SLC6A4 (0.52) | CTSCSLC6A4SLC6A2SLC6A3PPARG | |
| SCHEMBL11357662 | 0.66 | CTSC (0.45) | CTSCPPARGPPARALMNAHTT | |
| SCHEMBL11351984 | 0.64 | CTSC (0.43) | CTSCPPARGPPARALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994019363-A1 | PROCESS FOR PREPARING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |