Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | EEF2K | O00418 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923587 | 0.76 | GGPS1 (0.43) | GGPS1CA1CA14HTT | |
| SCHEMBL1095213 | 0.76 | ALDH1A1 (0.45) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL10994456 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL9394012 | 0.72 | ALDH1A1 (0.38) | GGPS1MAPTALDH1A1GAALMNA | |
| SCHEMBL11857458 | 0.70 | LMNA (0.49) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL11862705 | 0.70 | ESR1 (0.48) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL11861718 | 0.70 | ALDH1A1 (0.43) | GGPS1MAPTALDH1A1GAALMNA | |
| SCHEMBL9863585 | 0.70 | LMNA (0.44) | MAPTALDH1A1GAALMNAPOLB | |
| SCHEMBL1097210 | 0.69 | USP2 (0.44) | ALDH1A1GAALMNAPOLBEEF2K | |
| SCHEMBL8922306 | 0.69 | CTSC (0.41) | LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |