Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 5/20 | 0.44 |
| ▸ | ANPEP | P15144 | 3/20 | 0.44 |
| ▸ | ACP3 | P15309 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 4/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922306 | 0.85 | CTSC (0.41) | ACP3CTSCCYP1A2 | |
| SCHEMBL1343851 | 0.75 | EPHX1 (0.48) | ANPEPCTSCCTSSCTSKCYP1A2 | |
| SCHEMBL353200 | 0.72 | TRPA1 (0.48) | ANPEPCTSCCTSSCTSLCTSK | |
| SCHEMBL4107089 | 0.71 | LAP3 (0.55) | LAP3ANPEPACP3CTSCCYP1A2 | |
| SCHEMBL11252980 | 0.69 | CTSC (0.47) | ANPEPCTSC | |
| SCHEMBL31118140 | 0.69 | CTSC (0.46) | CTSCCTSSCTSK | |
| SCHEMBL6681928 | 0.68 | ALPL (0.47) | LAP3ANPEPACP3CTSLCTSB | |
| SCHEMBL10701497 | 0.67 | EPHX1 (0.40) | LAP3ANPEPCTSCCTSSCTSK | |
| SCHEMBL11040175 | 0.67 | CTSS (0.44) | ANPEPCTSCCTSSCTSLCTSK | |
| SCHEMBL2086061 | 0.66 | TDP1 (0.40) | ANPEPCTSCCTSSCTSKCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5644048-A | Process for preparing phosphorothioate oligonucleotides | ISIS PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| WO-1994019363-A1 | PROCESS FOR PREPARING PHOSPHOROTHIOATE OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1994-09-01 | — | — | WO | disclosed |
| US-5210264-A | S-(2,4-dichlorobenzyl)-β-cyanoethyl phosphorothioate diester | ISIS PHARMACEUTICALS, INC. (US) | 1993-05-11 | — | — | US | disclosed |