Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | DNM2 | P50570 | 4/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 2/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2066722 | 0.77 | KDM4E (0.36) | GAAMEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL1747638 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL1385358 | 0.76 | — | — | |
| SCHEMBL5622381 | 0.74 | ALDH1A1 (0.62) | CYP2C19HRH3KAT2BDNM2HRH4 | |
| SCHEMBL8925291 | 0.71 | ALDH1A1 (0.39) | MEN1KMT2APOLB | |
| SCHEMBL933058 | 0.69 | CYP2D6 (0.38) | CYP2C19HRH3CYP2D6CHRM2SLC6A2 | |
| SCHEMBL1963739 | 0.69 | — | — | |
| SCHEMBL933811 | 0.69 | — | — | |
| SCHEMBL4440939 | 0.68 | CYP2C19 (1.00) | CYP2C19HRH3DNM2GAAALPG | |
| SCHEMBL29943771 | 0.68 | CYP2C19 (1.00) | CYP2C19HRH3DNM2GAAALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |