Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021551 | 0.83 | EGLN2 (0.38) | KMT2AKDM4ESHMT2POLBMEN1 | |
| SCHEMBL2066722 | 0.79 | KDM4E (0.36) | ALDH1A1KMT2AKDM4EPOLBMEN1 | |
| SCHEMBL17234481 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KMT2AHSD17B10HPGDKDM4E | |
| SCHEMBL8922325 | 0.71 | CYP2C19 (0.51) | KMT2APOLBMEN1 | |
| SCHEMBL1747638 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1385358 | 0.71 | — | — | |
| SCHEMBL8924497 | 0.70 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SHMT2 | |
| SCHEMBL2648906 | 0.69 | FABP1 (0.53) | ALDH1A1KMT2AHPGDKDM4EMEN1 | |
| SCHEMBL243759 | 0.69 | ITGB3 (0.63) | ALDH1A1KMT2AHSD17B10HPGDMEN1 | |
| SCHEMBL6647364 | 0.68 | MEN1 (0.44) | ALDH1A1KMT2AHSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |