SCHEMBL8922452

SCHEMBL8922452

COc1ccc(O)c2ccc(-c3ccccc3)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 2/20 0.51
CCND1 P24385 2/20 0.51
CHEK1 O14757 1/20 0.51
FGFR1 P11362 1/20 0.51
CCNA2 P20248 1/20 0.51
CDK2 P24941 1/20 0.51
CCND3 P30281 1/20 0.51
KDR P35968 1/20 0.51
ALOX5 P09917 1/20 0.48
NQO1 P15559 1/20 0.47
ACLY P53396 2/20 0.47
ABCC1 P33527 1/20 0.46
WDR5 P61964 1/20 0.45
FYN P06241 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 2/20 0.44
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11425082 0.82 ALOX5 (0.64) ALOX5MEN1KMT2AKDM4EUSP2
SCHEMBL30957832 0.80 POLB (0.62) CDK4CCND1CHEK1FGFR1CCNA2
SCHEMBL27619310 0.80 ALOX5 (0.57) ALOX5ACLYABCC1MEN1KMT2A
SCHEMBL2524920 0.80 POLB (0.62) CDK4CCND1CHEK1FGFR1CCNA2
SCHEMBL9628047 0.80 TDO2 (0.48) CDK4CCND1CHEK1FGFR1CCNA2
SCHEMBL9658181 0.79 ABCC1 (0.48) CDK4CCND1CHEK1FGFR1CCNA2
SCHEMBL9379302 0.78 FYN (0.52) CDK4CCND1CHEK1FGFR1CCNA2
SCHEMBL217255 0.78 IDO1 (0.59) NQO1MEN1KMT2APOLBKDM4E
SCHEMBL8925401 0.77 ALOX5 (0.53) ALOX5MEN1KMT2AKDM4EUSP2
SCHEMBL8922610 0.76 IDH1 (0.53) NQO1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP claimed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP claimed
US-5663032-A NAPHTHOL DERIVATIVE REDUCING AGENT CANON KABUSHIKI KAISHA (JP) 1997-09-02 US disclosed
EP-0332455-B1 Photosensitive material and image forming method CANON KK (JP) 1996-06-05 EP disclosed
EP-0330504-B1 Photosensitive material and image forming method CANON KK (JP) 1996-05-22 EP disclosed
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
EP-0653680-A2 Photosensitive composition, photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1995-05-17 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed
US-5260164-A Silver halide, organic silver salt, cyclic reducing agent, the above compounds adapted to provide imagewise oxidized product of reducing agent upon imagewise exposure and heat development, polymer precursor, photopolymerization initiator CANON KABUSHIKI KAISHA (JP) 1993-11-09 US disclosed
US-5064744-A Heat, photopolymerization, silver halide contrast CANON KABUSHIKI KAISHA (JP) 1991-11-12 US disclosed
US-5041369-A Silver Halide, Silver Salt, Reducing Agent, Metal or Organic Dye CANON KABUSHIKI KAISHA (JP) 1991-08-20 US disclosed
EP-0360014-A1 Photosensitive material and image forming method using same CANON KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0330504-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-30 EP disclosed
EP-0326424-A2 Photosensitive composition, photosensitive material, and image forming method CANON KABUSHIKI KAISHA (JP) 1989-08-02 EP disclosed