Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.30 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2946259 | 1.00 | TDP1 (0.38) | TDP1USP2ALDH1A1HPGDLMNA | |
| SCHEMBL1778280 | 0.85 | HSP90AA1 (0.33) | HDAC1 | |
| SCHEMBL293129 | 0.79 | HRH1 (0.35) | HDAC1HRH1 | |
| SCHEMBL18222819 | 0.78 | FAAH (0.42) | TDP1 | |
| SCHEMBL28362525 | 0.78 | HSP90AA1 (0.40) | HDAC1TSHRHRH1XDHTLR7 | |
| SCHEMBL294018 | 0.77 | HSP90AA1 (0.33) | HDAC1HRH1 | |
| SCHEMBL5138548 | 0.76 | TDP1 (0.47) | TDP1USP2ALDH1A1HPGDLMNA | |
| SCHEMBL15376927 | 0.76 | TDP1 (0.47) | TDP1USP2ALDH1A1HPGDLMNA | |
| SCHEMBL734958 | 0.76 | TDP1 (0.47) | TDP1USP2ALDH1A1HPGDLMNA | |
| SCHEMBL16115136 | 0.76 | TDP1 (0.47) | TDP1USP2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646098-A | Carbonyl containing compounds and their derivatives as multi-functional fuel and lube additives | EXXON CHEMICAL PATENTS INC (US) | 1997-07-08 | — | — | US | disclosed |
| US-5550241-A | Adducts of cyclic carbonyl monomers and substituted alkens | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1996-08-27 | — | — | US | disclosed |