Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 4/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.36 |
| ▸ | FABP7 | O15540 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923888 | 0.84 | SMN1; SMN2 (0.44) | KMT2A | |
| SCHEMBL17753728 | 0.73 | KMT2A (0.54) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL7037298 | 0.73 | KMT2A (0.54) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL31742570 | 0.71 | EPHX2 (0.44) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL23156931 | 0.71 | EPHX2 (0.44) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL28365887 | 0.70 | EPHX2 (0.46) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL31278506 | 0.70 | FABP5 (0.38) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL18154894 | 0.69 | EPHX2 (0.43) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL2583781 | 0.69 | EPHX2 (0.43) | EPHX2KMT2ACASP3FABP5FABP7 | |
| SCHEMBL2583787 | 0.69 | EPHX2 (0.43) | EPHX2KMT2ACASP3FABP5FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616573-A | Glucocorticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-04-01 | — | — | US | disclosed |
| EP-0693080-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |
| WO-1994022898-A1 | NEW GLUCOCORTICOIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-10-13 | — | — | WO | disclosed |