Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 2/20 | 0.57 |
| ▸ | PNP | P00491 | 7/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HPRT1 | P00492 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922752 | 0.84 | TK1 (0.52) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL9369448 | 0.83 | TK1 (0.59) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL10836051 | 0.83 | TK1 (0.59) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL18661616 | 0.83 | TK1 (0.52) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL20977457 | 0.83 | TK1 (0.52) | TK1PNPBLMUSP2TSHR | |
| SCHEMBL8104283 | 0.83 | ALDH1A1 (0.70) | TK1PNPALDH1A1LMNAHPRT1 | |
| SCHEMBL3162 | 0.83 | ALDH1A1 (0.70) | TK1PNPALDH1A1LMNAHPRT1 | |
| SCHEMBL13833316 | 0.83 | ALDH1A1 (0.70) | TK1PNPALDH1A1LMNAHPRT1 | |
| SCHEMBL16695889 | 0.83 | ALDH1A1 (0.70) | TK1PNPALDH1A1LMNAHPRT1 | |
| SCHEMBL19325461 | 0.83 | ALDH1A1 (0.70) | TK1PNPALDH1A1LMNAHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703224-A | Antiviral c-nucleoside derivatives | NIPPON SHINYAKU CO. LTD. (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0733630-A1 | NUCLEOSIDE DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1996-09-25 | — | — | EP | disclosed |