Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6081429 | 0.73 | KDM4E (0.42) | GAAGSK3AGSK3BSMN1; SMN2KDM4E | |
| SCHEMBL17104893 | 0.66 | RAB9A (0.55) | GAAMAPK1SMN1; SMN2KDM4EEP300 | |
| SCHEMBL28379997 | 0.66 | SMN1; SMN2 (0.55) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL14446897 | 0.66 | SLC11A2 (0.52) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL7601190 | 0.66 | CHEK1 (0.58) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL565271 | 0.66 | SMN1; SMN2 (0.53) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL8686617 | 0.64 | RAB9A (0.45) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL14041252 | 0.64 | SLC11A2 (0.94) | GAAMAPK1SLC11A2KDM4E | |
| SCHEMBL11411739 | 0.63 | GAA (1.00) | GAAMAPK1CHEK1AURKADAPK3 | |
| SCHEMBL7479419 | 0.63 | ALDH1A1 (0.73) | GAASMN1; SMN2KDM4EEP300KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | claimed |
| EP-0692482-A2 | 1-pyridyltetrazolinone derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1996-01-17 | — | — | EP | claimed |
| CN-1224014-A | Pyridyltetrazolinone derivatives | BAYER AGROCHEM KK (JP) | 1999-07-28 | — | — | CN | disclosed |