SCHEMBL11411739

SCHEMBL11411739

O=c1[nH]n(-c2ccccn2)c(=O)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 1.00
MAPK1 P28482 1/20 1.00
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
HPGD P15428 1/20 0.56
CYP2C19 P33261 1/20 0.56
TSHR P16473 1/20 0.56
SLC11A2 P49281 7/20 0.54
KDM4E B2RXH2 3/20 0.54
LDHA P00338 1/20 0.51
CHEK1 O14757 1/20 0.51
AURKA O14965 1/20 0.51
DAPK3 O43293 1/20 0.51
JAK2 O60674 1/20 0.51
PRKD3 O94806 1/20 0.51
MAP4K4 O95819 1/20 0.51
PAK4 O96013 1/20 0.51
ABL1 P00519 1/20 0.51
NTRK1 P04629 1/20 0.51
FYN P06241 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30484385 0.75 GAA (0.60) GAAMAPK1CYP1A2CYP3A4HPGD
SCHEMBL14041252 0.72 SLC11A2 (0.94) GAAMAPK1SLC11A2KDM4E
SCHEMBL29831050 0.72 HPGD (1.00) GAAMAPK1CYP1A2CYP3A4HPGD
SCHEMBL17552213 0.72 HPGD (1.00) GAAMAPK1CYP1A2CYP3A4HPGD
SCHEMBL31384289 0.72 TSHR (1.00) GAAMAPK1CYP1A2CYP3A4HPGD
SCHEMBL265111 0.72 TSHR (1.00) GAAMAPK1CYP1A2CYP3A4HPGD
SCHEMBL7601190 0.71 CHEK1 (0.58) GAAMAPK1SLC11A2KDM4ECHEK1
SCHEMBL30484349 0.71 GAA (0.55) GAAMAPK1CYP1A2HPGDCYP2C19
SCHEMBL2567610 0.70 GABRA1 (0.59) GAAMAPK1CYP1A2CYP2C19SLC11A2
SCHEMBL10551890 0.70 SLC11A2 (1.00) GAAMAPK1SLC11A2KDM4ENOX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US claimed
US-4207112-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1980-06-10 US disclosed
US-4076534-A Heat developable light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed