Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 11/20 | 0.43 |
| ▸ | PPARD | Q03181 | 8/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922791 | 1.00 | PPARA (0.45) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8923395 | 0.87 | ADRB3 (0.45) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8923401 | 0.87 | ADRB3 (0.45) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8923974 | 0.81 | PPARG (0.52) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8924029 | 0.77 | PPARG (0.64) | PPARAPPARGPPARD | |
| SCHEMBL9517990 | 0.76 | CA2 (0.55) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8923846 | 0.74 | PPARG (0.59) | PPARAPPARGPPARD | |
| Tert-Butylamine SCHEMBL8924048 | 0.74 | PPARG (0.43) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8924650 | 0.74 | ADRB3 (0.43) | PPARAMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8924642 | 0.74 | ADRB3 (0.43) | PPARAMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627205-A | ANTILIPEMIC AGENTS AND ANTIOXIDANTS | ADIR ET COMPAGNIE (FR) | 1997-05-06 | — | — | US | disclosed |