Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955987 | 0.80 | TSHR (0.36) | TSHR | |
| SCHEMBL1178580 | 0.76 | TSHR (0.41) | TSHR | |
| SCHEMBL10605319 | 0.74 | MAPT (0.42) | ALDH1A1MAPTTSHR | |
| SCHEMBL10605323 | 0.74 | MAPT (0.42) | ALDH1A1MAPTTSHR | |
| SCHEMBL10649967 | 0.74 | TSHR (0.39) | TSHR | |
| SCHEMBL14945 | 0.74 | LMNA (0.43) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL4219082 | 0.74 | TSHR (0.42) | MAPTTSHRMAPK1 | |
| SCHEMBL8853633 | 0.74 | TSHR (0.42) | MAPTTSHRMAPK1 | |
| SCHEMBL27606246 | 0.73 | TSHR (0.34) | USP2ALDH1A1CYP3A4MAPTHPGD | |
| SCHEMBL873047 | 0.72 | TSHR (0.59) | ALDH1A1MAPTHPGDSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591563-A | POLYACRYLATED DIURETHANE, ACRYLOYLMORPHOLINE | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1997-01-07 | — | — | US | disclosed |